• Adults Only Website 18+

    If you are under 18 you are not permitted to submit personal information to us or use this website. If discovered you will be banned.

    We will ban and report anyone posting illegal content.

    We will ban any forum user who breaks our terms.

    Freedom of speech should be wide open as long as it doesn't incite violence.

    We have a 15 year old thriving community here with 400,000+ members and hundreds of people online at any given moment, we encourage you to join!, there are 1000's of topics to discuss. Please be aware before registering and read our terms of service and privacy policy.

    By dismissing this notice and proceeding, you agree to the above.

Another Random Mouth Fact- Pain Killer Stronger Than Morphine Made In Our Spit

This isn’t a new finding. It was made public around 2006, but hasn’t been widely cited or had much media attention. So I thought some of you nutters might like to know about it. I will say this now, I don’t think snorting your own spit will get you high!

Opiorphin is the name of the pain killing compound found in human salvia. It was shown to be up to 6 times stronger than morphine in some barbaric tests on rats (described in the JAMA link below).

It works by preventing to breakdown of our own natural opioids, the enkephalins (aka endorphins). So it doesn’t directly stimulate the pain relieving opioid receptors, it enhances them.

It makes sense from an evolutionary perspective. Our mouth has The power of a rugby team as we have seen. Our tongue is awash with sensory nerves. Accidentally biting our tongue, like having a rugby player stand on your tongue, hurts like fuck. So our spit/ saliva/ greb helps us chill out the pain.

Chewing our food causes trauma to the inside of the mouth on a frequent basis, but we keep enjoying it. Thanks opiorphin!

JAMA Net Link

I’m sure there will be a man made version of this analgesic at some point. There hasn’t been much data published since its discovery so when this happens is up to God, or possibly @ZeroK as he’s similar to the former.

Have another nice evening. 😎
 
This isn’t a new finding. It was made public around 2006, but hasn’t been widely cited or had much media attention. So I thought some of you nutters might like to know about it. I will say this now, I don’t think snorting your own spit will get you high!

Opiorphin is the name of the pain killing compound found in human salvia. It was shown to be up to 6 times stronger than morphine in some barbaric tests on rats (described in the JAMA link below).

It works by preventing to breakdown of our own natural opioids, the enkephalins (aka endorphins). So it doesn’t directly stimulate the pain relieving opioid receptors, it enhances them.

It makes sense from an evolutionary perspective. Our mouth has The power of a rugby team as we have seen. Our tongue is awash with sensory nerves. Accidentally biting our tongue, like having a rugby player stand on your tongue, hurts like fuck. So our spit/ saliva/ greb helps us chill out the pain.

Chewing our food causes trauma to the inside of the mouth on a frequent basis, but we keep enjoying it. Thanks opiorphin!

JAMA Net Link

I’m sure there will be a man made version of this analgesic at some point. There hasn’t been much data published since its discovery so when this happens is up to God, or possibly @ZeroK as he’s similar to the former.

Have another nice evening. 😎
Very interesting! I didn't know that; But I luv to learn New Shit! Thanks Bro!👍
🤘🤟🤙...SP
 
So THATS why I use my spit as lube, out of love and decency!

Thanks for the post, I never would have thought my spit would be riddled with something stronger than morphine, that's really interesting, I'll deffs be reading that article
 
This isn’t a new finding. It was made public around 2006, but hasn’t been widely cited or had much media attention. So I thought some of you nutters might like to know about it. I will say this now, I don’t think snorting your own spit will get you high!

Opiorphin is the name of the pain killing compound found in human salvia. It was shown to be up to 6 times stronger than morphine in some barbaric tests on rats (described in the JAMA link below).

It works by preventing to breakdown of our own natural opioids, the enkephalins (aka endorphins). So it doesn’t directly stimulate the pain relieving opioid receptors, it enhances them.

It makes sense from an evolutionary perspective. Our mouth has The power of a rugby team as we have seen. Our tongue is awash with sensory nerves. Accidentally biting our tongue, like having a rugby player stand on your tongue, hurts like fuck. So our spit/ saliva/ greb helps us chill out the pain.

Chewing our food causes trauma to the inside of the mouth on a frequent basis, but we keep enjoying it. Thanks opiorphin!

JAMA Net Link

I’m sure there will be a man made version of this analgesic at some point. There hasn’t been much data published since its discovery so when this happens is up to God, or possibly @ZeroK as he’s similar to the former.

Have another nice evening. 😎
Cool info brother.
 
It Definitely Helps With Pain
78AB3F5D-ADE0-4F50-A628-B7B187507035.webp
 
speaking of tongues,i have a geographical tongue.

So do I. Interestingly, I keep mine at bay by having some 70% Carolina Reaper Psycho Juice daily. I initially started using hot sauces to keep the substance P (pain transmitter) level down to reduce the pain. Clearly my Opiorphin wasn’t up to the job. To my surprise the very hot sauces actually cure it, and it comes back if I don’t have hot sauce for more than a few days.
 
So do I. Interestingly, I keep mine at bay by having some 70% Carolina Reaper Psycho Juice daily. I initially started using hot sauces to keep the substance P (pain transmitter) level down to reduce the pain. Clearly my Opiorphin wasn’t up to the job. To my surprise the very hot sauces actually cure it, and it comes back if I don’t have hot sauce for more than a few days.
mine doesnt hurt or irritate really much. if anything,it will irritate if i have food thats high in acid content. as for spicy food,i dont eat really much of that. but when i do,it doesnt bother it. i guess because i rarely eat any. as for salty stuff,i barely use that as well. im fine with bland/plain. i dont need bp problems in the future. we are in a low percentile with this "condition". its not a common thing. at first i thought something was wrong when i discovered this. one side was "patchy". then later,it was the other side. then the front. then its like it went away. then it would come back and it would be the middle of my tongue. its always shifting. crazy how the body works.
 
Back
Top