It's known as the deadly fungus credited with killing the archaeologists who opened the tomb of King Tut.
Now, University of Pennsylvania researchers say they've transformed it into a promising treatment for cancer.
Aspergillus flavus is a toxic yellow-spored fungus that likely entered and flourished in the lungs of the crew members who untombed the Egyptian pharaoh in the 1920s.
After isolating a new class of molecules from the fungus, researchers were able to, in short, modify their chemical outlook.
When mixed with human cancer cells, those modified cells demonstrated medical potential, as two of the four variants had potent effects against leukemia cells, preventing them from dividing.
The next step is to test those compounds in animals with the hope of one day moving to human clinical trials.
“Nature has given us this incredible pharmacy,” said Sherry Gao, an associate professor in Chemical and Biomolecular Engineering and Bioengineering at the University of Pennsylvania. “It’s up to us to uncover its secrets. As engineers, we’re excited to keep exploring, learning from nature and using that knowledge to design better solutions."
You can read the full findings from Penn researchers here.
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Now, University of Pennsylvania researchers say they've transformed it into a promising treatment for cancer.
Aspergillus flavus is a toxic yellow-spored fungus that likely entered and flourished in the lungs of the crew members who untombed the Egyptian pharaoh in the 1920s.
After isolating a new class of molecules from the fungus, researchers were able to, in short, modify their chemical outlook.
When mixed with human cancer cells, those modified cells demonstrated medical potential, as two of the four variants had potent effects against leukemia cells, preventing them from dividing.
The next step is to test those compounds in animals with the hope of one day moving to human clinical trials.
“Nature has given us this incredible pharmacy,” said Sherry Gao, an associate professor in Chemical and Biomolecular Engineering and Bioengineering at the University of Pennsylvania. “It’s up to us to uncover its secrets. As engineers, we’re excited to keep exploring, learning from nature and using that knowledge to design better solutions."
You can read the full findings from Penn researchers here.
Toxic fungus tied to King Tut's tomb shows promise as leukemia treatment, Penn researchers find
The deadly fungus credited with killing the archaeologists that opened the tomb of King Tut might become a treatment for cancer




